cyclic neutropenia การใช้

• Collies may have a genetic disease, canine cyclic neutropenia, or Grey Collie Syndrome.
• Canine cyclic neutropenia is a cyclic blood disorder that is usually fatal to affected puppies.
• Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia ( SCN ).
• Other investigations commonly performed : serial neutrophil counts for suspected cyclic neutropenia, tests for vitamin B 12 and folate assays.
• Aphthous-like ulceration also occurs in conditions involving systemic immuno-dysregulation, e . g . cyclic neutropenia and human immunodeficiency virus infection.
• In cyclic neutropenia, more severe oral ulceration occurs during periods of severe immuno-dysregulation, and resolution of the underlying neutropenia prevents the cycle of ulceration.
• In cyclic neutropenia, there is a reduction in the level of circulating neutrophils in the blood that occurs about every 21 days . Opportunistic infections commonly occur and aphthous-like ulceration is worst during this time.